Educational Wellness Information Only

This platform provides peer-reviewed research summaries and educational content about peptides for wellness and optimization purposes. Nothing on this site is intended as medical advice, diagnosis, or treatment. We do not claim any peptide can diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any wellness protocol.

Statements on this site have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability and eligibility vary.

Counter-regulatory Hormone · Endocrine

Glucagon (GlucaGen / Baqsimi)

29-amino-acid peptide hormone for severe hypoglycemia.

FDA-Approved

Plain-Language Label Highlights

Brand names: GlucaGen, Baqsimi (nasal), Gvoke (auto-injector)

What it's approved for

Severe low blood sugar in people with diabetes; also used to relax GI smooth muscle for imaging.

An emergency treatment (injection or nasal powder) that quickly raises blood sugar when someone with diabetes is unable to eat or drink.

Common side effects

•Nausea/vomiting after recovery
•Headache
•Nasal irritation (Baqsimi)

Serious risks to know

•Severe allergic reactions
•Necrolytic migratory erythema with prolonged infusion
•Caution in pheochromocytoma, insulinoma, glucagonoma

Who should avoid or use with extra caution

•Pheochromocytoma
•Insulinoma
•Known glucagonoma

Educational summary of the FDA prescribing information. Not a substitute for the full label or medical advice. Always discuss with a licensed prescriber.

Mechanism of Action

Pancreatic alpha-cell peptide hormone that activates hepatic glucagon receptors, stimulating glycogenolysis and gluconeogenesis to raise blood glucose; also relaxes GI smooth muscle (used in radiology).

Research Areas

Severe hypoglycemia (T1D/T2D)

Beta-blocker overdose

GI motility (imaging adjunct)

Common Research Protocols

Hypoglycemia (IM)

1 mg IM/SC; pediatric weight-based.

Nasal (Baqsimi)

3 mg single intranasal dose.

Protocols summarized for educational reference from published research. Not dosing guidance.

Cited Research

[1]Diabetes Care·2016

Nasal glucagon (Baqsimi) trials

Non-inferior glucose response vs IM glucagon, easier administration.

Important Considerations

•FDA-approved.
•Nausea/vomiting common after recovery.

Explore more peptides

Educational Information Only — Not Medical Advice

All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.

Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.

Searching the library…

Ask the Library

Ask anything about peptides — answers come from our curated reference library with citations.