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AOD-9604 Peptide
Modified GH fragment researched for adipose tissue effects.
What is AOD-9604?
AOD-9604 is a metabolic · lipolysis peptide studied for obesity (clinical trials did not meet endpoints) and osteoarthritis / cartilage repair (current research direction). Below is an educational overview of AOD-9604 peptide benefits, mechanism, common research protocols, dosage references, and known side effects.
AOD-9604 in plain language
AOD-9604 is a metabolic · lipolysis peptide. Modified GH fragment researched for adipose tissue effects.
- Classification: Fat loss.
- Category: Metabolic · Lipolysis.
- Proposed mechanism: A modified 16-amino-acid fragment (177–191) of human growth hormone, engineered to retain the lipolytic activity of GH without its growth or insulin-resistance effects. Research suggests it stimulates lipolysis and inhibits lipogenesis.
- Commonly researched areas: obesity (clinical trials did not meet endpoints), osteoarthritis / cartilage repair (current research direction), localized adipose research.
- Research context: Subcutaneous research — Daily subcutaneous dosing in early clinical and animal lipolysis studies.
- Key consideration: Not FDA-approved as a therapeutic.
- Educational summary only; this page is not medical advice and does not describe a treatment protocol.
Machine-readable version: /peptide/aod-9604/summary
AOD-9604 Mechanism of Action
A modified 16-amino-acid fragment (177–191) of human growth hormone, engineered to retain the lipolytic activity of GH without its growth or insulin-resistance effects. Research suggests it stimulates lipolysis and inhibits lipogenesis.
AOD-9604 Research Areas & Benefits
AOD-9604 Dosage & Common Research Protocols
Daily subcutaneous dosing in early clinical and animal lipolysis studies.
Protocols summarized for educational reference from published research. Not dosing guidance.
AOD-9604 Studies & Cited Research
AOD9604 in obesity: phase 2b results
Did not achieve significant weight loss vs. placebo in primary endpoint.
Why we trust this source: Published in a peer-reviewed scientific journal with editorial and reviewer oversight.
Citations are linked to PubMed, Google Scholar, and Crossref searches so you can verify the source independently. All references are reviewed during our editorial passes (last reviewed June 1, 2026).
AOD-9604 Side Effects & Safety Considerations
- •Not FDA-approved as a therapeutic.
- •Has GRAS status in some food contexts (Australia), not equivalent to drug approval.
Common questions about AOD-9604
More Fat loss peptides · See all 14
Educational Information Only — Not Medical Advice
All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.
Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.
Key references for AOD-9604
Primary sources reviewed by the Peptides.cafe research team. Links open the original PubMed record, journal listing, or regulatory notice.
- [1]The effect of AOD9604 on body composition in obese subjectsObesity Research / clinical program reports · 2004
Human trial that failed to separate from placebo on the primary weight endpoint.
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