# AOD-9604

> Modified GH fragment researched for adipose tissue effects.

Source: https://peptides.cafe/peptide/aod-9604
Category: Metabolic · Lipolysis
Tag: Fat loss

## Mechanism
A modified 16-amino-acid fragment (177–191) of human growth hormone, engineered to retain the lipolytic activity of GH without its growth or insulin-resistance effects. Research suggests it stimulates lipolysis and inhibits lipogenesis.

## Research areas
- Obesity (clinical trials did not meet endpoints)
- Osteoarthritis / cartilage repair (current research direction)
- Localized adipose research

## Common research protocols
- Subcutaneous research: Daily subcutaneous dosing in early clinical and animal lipolysis studies.

## Study summaries
- "AOD9604 in obesity: phase 2b results" — Obesity (2010): Did not achieve significant weight loss vs. placebo in primary endpoint.

## Considerations
- Not FDA-approved as a therapeutic.
- Has GRAS status in some food contexts (Australia), not equivalent to drug approval.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.