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This platform provides peer-reviewed research summaries and educational content about peptides for wellness and optimization purposes. Nothing on this site is intended as medical advice, diagnosis, or treatment. We do not claim any peptide can diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any wellness protocol.
Statements on this site have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability and eligibility vary.
Triptorelin (Trelstar) Peptide
GnRH agonist depot for advanced prostate cancer.
What is Triptorelin (Trelstar)?
Triptorelin (Trelstar) is a gnrh agonist · oncology peptide studied for advanced prostate cancer and central precocious puberty (international). Below is an educational overview of Triptorelin (Trelstar) peptide benefits, mechanism, common research protocols, dosage references, and known side effects.
Plain-Language Label Highlights
Brand names: Trelstar, Triptodur
Advanced prostate cancer (Trelstar) and central precocious puberty (Triptodur).
A depot injection that suppresses sex hormones — used long-term in advanced prostate cancer or to pause early puberty.
- •Hot flashes
- •Erectile dysfunction
- •Injection-site pain
- •Skeletal pain (initial flare)
- •Initial testosterone flare worsening symptoms
- •Cardiovascular disease and stroke
- •Hyperglycemia and diabetes
- •QT prolongation
- •Convulsions
- •Pregnancy
- •Known hypersensitivity to GnRH agonists
Educational summary of the FDA prescribing information. Not a substitute for the full label or medical advice. Always discuss with a licensed prescriber.
Triptorelin (Trelstar) Mechanism of Action
Decapeptide GnRH agonist that initially stimulates then desensitizes pituitary GnRH receptors, suppressing LH, FSH, and downstream gonadal steroid production after the initial flare.
Triptorelin (Trelstar) Research Areas & Benefits
Triptorelin (Trelstar) Dosage & Common Research Protocols
3.75 mg monthly, 11.25 mg every 3 months, or 22.5 mg every 6 months IM.
Protocols summarized for educational reference from published research. Not dosing guidance.
Triptorelin (Trelstar) Studies & Cited Research
Triptorelin vs leuprolide in prostate cancer
Comparable testosterone suppression efficacy.
Why we trust this source: Source not yet matched to our reputable list. Treat as background information only.
Citations are linked to PubMed, Google Scholar, and Crossref searches so you can verify the source independently. All references are reviewed during our editorial passes (last reviewed June 1, 2026).
Triptorelin (Trelstar) Side Effects & Safety Considerations
- •FDA-approved.
- •Initial testosterone flare; consider antiandrogen pretreatment.
- •Hot flashes, bone density loss with chronic use.
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Educational Information Only — Not Medical Advice
All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.
Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.
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