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Statements on this site have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability and eligibility vary.

GH Analog · Endocrine

Somapacitan (Sogroya)

Once-weekly growth hormone analog for adults and children with GHD.

FDA-Approved

Plain-Language Label Highlights

Brand names: Sogroya

What it's approved for

Growth hormone deficiency in adults and children 2.5 years and older.

A once-weekly growth hormone injection (alternative to daily) for adults and kids with GH deficiency.

Common side effects
  • Headache
  • Back pain
  • Joint pain
  • Peripheral edema
  • Vomiting (pediatric)
Serious risks to know
  • Intracranial hypertension
  • Pancreatitis
  • Adrenal insufficiency unmasking
  • Increased mortality if used in acute critical illness
  • Slipped capital femoral epiphysis
Who should avoid or use with extra caution
  • Active malignancy
  • Acute critical illness
  • Hypersensitivity to somapacitan

Educational summary of the FDA prescribing information. Not a substitute for the full label or medical advice. Always discuss with a licensed prescriber.

Mechanism of Action

GH analog with a non-covalent albumin-binding side chain that extends half-life, enabling once-weekly subcutaneous administration with sustained IGF-1 elevation.

Research Areas

Adult growth hormone deficiency
Pediatric GH deficiency

Common Research Protocols

Weekly SC

Adults: 1.5 mg weekly start, titrate by IGF-1. Pediatric: 0.16 mg/kg weekly.

Protocols summarized for educational reference from published research. Not dosing guidance.

Cited Research

[1]JCEM·2020

REAL trials

Comparable body composition and IGF-1 response to daily somatropin.

Important Considerations

  • FDA-approved.
  • Monitor glucose; injection-site reactions possible.

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Educational Information Only — Not Medical Advice

All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.

Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.

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