# Somapacitan (Sogroya)

> Once-weekly growth hormone analog for adults and children with GHD.

Source: https://peptides.cafe/peptide/somapacitan
Category: GH Analog · Endocrine
Tag: FDA-Approved · Endocrine

## Mechanism
GH analog with a non-covalent albumin-binding side chain that extends half-life, enabling once-weekly subcutaneous administration with sustained IGF-1 elevation.

## Research areas
- Adult growth hormone deficiency
- Pediatric GH deficiency

## Common research protocols
- Weekly SC: Adults: 1.5 mg weekly start, titrate by IGF-1. Pediatric: 0.16 mg/kg weekly.

## Study summaries
- "REAL trials" — JCEM (2020): Comparable body composition and IGF-1 response to daily somatropin.

## Considerations
- FDA-approved.
- Monitor glucose; injection-site reactions possible.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.