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Sincalide (Kinevac) Peptide
Synthetic C-terminal octapeptide of cholecystokinin for gallbladder imaging.
What is Sincalide (Kinevac)?
Sincalide (Kinevac) is a cck analog · diagnostics peptide studied for gallbladder ejection fraction (hida scan) and pancreatic secretion testing. Below is an educational overview of Sincalide (Kinevac) peptide benefits, mechanism, common research protocols, dosage references, and known side effects.
Plain-Language Label Highlights
Brand names: Kinevac
Gallbladder imaging (cholescintigraphy), pancreatic stimulation testing, small-bowel imaging adjunct.
A short IV infusion that makes the gallbladder squeeze so doctors can measure how well it empties.
- •Abdominal cramping
- •Nausea
- •Diarrhea
- •Urge to defecate
- •Severe cramping if pushed too fast
- •Allergic reactions (rare)
- •Suspected gallstone obstruction
- •Acute cholecystitis without imaging plan
- •Known hypersensitivity to sincalide
Educational summary of the FDA prescribing information. Not a substitute for the full label or medical advice. Always discuss with a licensed prescriber.
Sincalide (Kinevac) Mechanism of Action
Synthetic CCK-8 that binds CCK-A receptors on gallbladder smooth muscle, triggering contraction; used to assess gallbladder ejection fraction in cholescintigraphy.
Sincalide (Kinevac) Research Areas & Benefits
Sincalide (Kinevac) Dosage & Common Research Protocols
0.02 mcg/kg IV infused over 60 minutes (preferred to bolus to limit cramping).
Protocols summarized for educational reference from published research. Not dosing guidance.
Sincalide (Kinevac) Studies & Cited Research
Standardized sincalide cholescintigraphy guideline
Established 60-minute infusion as optimal for reproducible GBEF.
Why we trust this source: Source not yet matched to our reputable list. Treat as background information only.
Citations are linked to PubMed, Google Scholar, and Crossref searches so you can verify the source independently. All references are reviewed during our editorial passes (last reviewed June 1, 2026).
Sincalide (Kinevac) Side Effects & Safety Considerations
- •FDA-approved.
- •Abdominal cramping, nausea, diarrhea common; contraindicated in suspected gallstone obstruction.
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Educational Information Only — Not Medical Advice
All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.
Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.
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