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Insulin Glargine (Lantus)
Long-acting basal insulin analog for type 1 and type 2 diabetes.
Plain-Language Label Highlights
Brand names: Lantus, Basaglar, Toujeo, Semglee
Type 1 and type 2 diabetes — once-daily basal insulin.
A long-acting insulin that gives you a flat, ~24-hour background level of insulin between meals and overnight.
- •Low blood sugar (hypoglycemia)
- •Weight gain
- •Injection-site reactions
- •Lipohypertrophy
- •Severe hypoglycemia
- •Severe allergic reactions
- •Low potassium
- •Fluid retention/heart failure with TZDs
- •Active hypoglycemia
- •Known insulin glargine hypersensitivity
Educational summary of the FDA prescribing information. Not a substitute for the full label or medical advice. Always discuss with a licensed prescriber.
Mechanism of Action
Recombinant human insulin analog with two arginine residues added to the B-chain and asparagine→glycine at A21, forming microprecipitates at injection site for ~24-hour glucose-lowering activity via insulin receptor activation.
Research Areas
Common Research Protocols
Subcutaneous injection once daily at the same time, titrated to fasting glucose.
Protocols summarized for educational reference from published research. Not dosing guidance.
Cited Research
Treat-to-target insulin glargine trials
Established efficacy and lower nocturnal hypoglycemia vs NPH insulin.
Important Considerations
- •FDA-approved.
- •Hypoglycemia and weight gain are primary risks.
- •Do not mix with other insulins.
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Educational Information Only — Not Medical Advice
All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.
Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.
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