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Immune comparison

LL-37 vs Thymogen

An educational, source-based comparison of LL-37 and Thymogen — how each peptide works, what it's researched for, and what to know before going deeper.

Immune · Antimicrobial
LL-37

Human cathelicidin peptide with antimicrobial and immune-modulating activity.

Mechanism

The only human cathelicidin antimicrobial peptide. Research demonstrates broad antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects on neutrophils, macrophages, and wound healing.

Research areas
  • Chronic biofilm infections
  • Wound healing and dermatology
  • Innate immune modulation
Considerations
  • Not FDA-approved.
  • Pro-inflammatory effects possible at higher doses.
Full LL-37 profile →
Immune · Bioregulator
Thymogen

Dipeptide bioregulator for immune system modulation.

Mechanism

A synthetic dipeptide (Glu-Trp) in the Khavinson bioregulator family. Research suggests modulation of thymic and immune cell gene expression, supporting T-cell maturation and innate immune response in aged models.

Research areas
  • Immunosenescence and age-related immune decline
  • Post-infectious immune recovery
  • Chronic fatigue and immune dysregulation
Considerations
  • Russian bioregulator research; limited independent replication.
  • Not FDA-approved.
Full Thymogen profile →

LL-37 vs Thymogen — Key differences

  • Class: LL-37 is classified as Immune · Antimicrobial, while Thymogen is Immune · Bioregulator.
  • Primary research focus: LL-37chronic biofilm infections; Thymogenimmunosenescence and age-related immune decline.
  • Tag: Immune · Antimicrobial vs Immune · Bioregulator.

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