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Statements on this site have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability and eligibility vary.
LL-37 Peptide
Human cathelicidin peptide with antimicrobial and immune-modulating activity.
What is LL-37?
LL-37 is a immune · antimicrobial peptide studied for chronic biofilm infections and wound healing and dermatology. Below is an educational overview of LL-37 peptide benefits, mechanism, common research protocols, dosage references, and known side effects.
LL-37 in plain language
LL-37 is a immune · antimicrobial peptide. Human cathelicidin peptide with antimicrobial and immune-modulating activity.
- Classification: Immune · Antimicrobial.
- Category: Immune · Antimicrobial.
- Proposed mechanism: The only human cathelicidin antimicrobial peptide. Research demonstrates broad antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects on neutrophils, macrophages, and wound healing.
- Commonly researched areas: chronic biofilm infections, wound healing and dermatology, innate immune modulation.
- Research context: Local and subcutaneous research — Investigational use in chronic infection and wound research.
- Key consideration: Not FDA-approved.
- Educational summary only; this page is not medical advice and does not describe a treatment protocol.
Machine-readable version: /peptide/ll-37/summary
LL-37 Mechanism of Action
The only human cathelicidin antimicrobial peptide. Research demonstrates broad antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects on neutrophils, macrophages, and wound healing.
LL-37 Research Areas & Benefits
LL-37 Dosage & Common Research Protocols
Investigational use in chronic infection and wound research.
Protocols summarized for educational reference from published research. Not dosing guidance.
LL-37 Studies & Cited Research
LL-37: a multifunctional host-defense peptide
Comprehensive review of antimicrobial and immunomodulatory roles.
Why we trust this source: Published in a peer-reviewed scientific journal with editorial and reviewer oversight.
Citations are linked to PubMed, Google Scholar, and Crossref searches so you can verify the source independently. All references are reviewed during our editorial passes (last reviewed June 1, 2026).
LL-37 Side Effects & Safety Considerations
- •Not FDA-approved.
- •Pro-inflammatory effects possible at higher doses.
Common questions about LL-37
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Educational Information Only — Not Medical Advice
All content on this page is for educational and informational purposes only. It is not medical advice, diagnosis, or treatment. We make no claims that any peptide can diagnose, treat, cure, or prevent any disease. Peptides discussed are not FDA-approved for the indications listed unless explicitly stated otherwise.
Always consult a licensed healthcare provider before beginning any wellness protocol. Statements have not been evaluated by the FDA. Compounded preparations are subject to applicable state and federal regulations. Availability, eligibility, and pricing may vary.
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