# LL-37 > Human cathelicidin peptide with antimicrobial and immune-modulating activity. Source: https://peptides.cafe/peptide/ll-37 Category: Immune · Antimicrobial Tag: Immune · Antimicrobial ## Mechanism The only human cathelicidin antimicrobial peptide. Research demonstrates broad antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects on neutrophils, macrophages, and wound healing. ## Research areas - Chronic biofilm infections - Wound healing and dermatology - Innate immune modulation ## Common research protocols - Local and subcutaneous research: Investigational use in chronic infection and wound research. ## Study summaries - "LL-37: a multifunctional host-defense peptide" — Frontiers in Immunology (2020): Comprehensive review of antimicrobial and immunomodulatory roles. ## Considerations - Not FDA-approved. - Pro-inflammatory effects possible at higher doses. ## Disclaimer Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.