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Immune comparison

LL-37 vs Thymalin

An educational, source-based comparison of LL-37 and Thymalin — how each peptide works, what it's researched for, and what to know before going deeper.

Immune · Antimicrobial
LL-37

Human cathelicidin peptide with antimicrobial and immune-modulating activity.

Mechanism

The only human cathelicidin antimicrobial peptide. Research demonstrates broad antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory effects on neutrophils, macrophages, and wound healing.

Research areas
  • Chronic biofilm infections
  • Wound healing and dermatology
  • Innate immune modulation
Considerations
  • Not FDA-approved.
  • Pro-inflammatory effects possible at higher doses.
Full LL-37 profile →
Immune · Bioregulator
Thymalin

Thymic peptide complex researched for immune restoration in aging.

Mechanism

A polypeptide complex extracted from calf thymus, studied as an immune bioregulator. Research suggests restoration of T-cell function and thymic activity in aged and immunocompromised cohorts.

Research areas
  • Immunosenescence
  • Recovery from infection in elderly cohorts
  • Adjunct in chronic inflammatory conditions
Considerations
  • Approved in Russia; not FDA-approved.
  • Mixture composition is not fully characterized.
Full Thymalin profile →

LL-37 vs Thymalin — Key differences

  • Class: LL-37 is classified as Immune · Antimicrobial, while Thymalin is Immune · Bioregulator.
  • Primary research focus: LL-37chronic biofilm infections; Thymalinimmunosenescence.
  • Tag: Immune · Antimicrobial vs Immune · Longevity.

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