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Performance comparison

Follistatin 344 vs Hexarelin

An educational, source-based comparison of Follistatin 344 and Hexarelin — how each peptide works, what it's researched for, and what to know before going deeper.

Muscle · Myostatin Inhibition
Follistatin 344

Myostatin-binding protein fragment researched for muscle growth.

Mechanism

A naturally occurring glycoprotein that binds and neutralizes myostatin and activin, releasing the natural brake on skeletal muscle growth in preclinical models.

Research areas
  • Muscular dystrophy models
  • Skeletal muscle hypertrophy
  • Age-related sarcopenia (preclinical)
Considerations
  • Off-target effects on activin signaling (reproductive, cardiac) are a concern.
  • Not FDA-approved; banned by WADA.
Full Follistatin 344 profile →
Growth Hormone Axis · Cardiac
Hexarelin

Potent ghrelin-mimetic with cardiac research interest.

Mechanism

A synthetic hexapeptide and potent GHS-R agonist. Stimulates GH release more strongly than GHRP-6 and shows cardioprotective signaling in preclinical ischemia-reperfusion models, partly independent of GH.

Research areas
  • GH release
  • Cardiac ischemia-reperfusion (preclinical)
  • Left ventricular function in animal models
Considerations
  • Not FDA-approved.
  • Tachyphylaxis with prolonged use.
  • Prohibited by WADA.
Full Hexarelin profile →

Follistatin 344 vs Hexarelin — Key differences

  • Class: Follistatin 344 is classified as Muscle · Myostatin Inhibition, while Hexarelin is Growth Hormone Axis · Cardiac.
  • Primary research focus: Follistatin 344muscular dystrophy models; Hexarelingh release.
  • Tag: Muscle vs Growth hormone.

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