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Performance comparison

Follistatin 344 vs GHRP-2

An educational, source-based comparison of Follistatin 344 and GHRP-2 — how each peptide works, what it's researched for, and what to know before going deeper.

Muscle · Myostatin Inhibition
Follistatin 344

Myostatin-binding protein fragment researched for muscle growth.

Mechanism

A naturally occurring glycoprotein that binds and neutralizes myostatin and activin, releasing the natural brake on skeletal muscle growth in preclinical models.

Research areas
  • Muscular dystrophy models
  • Skeletal muscle hypertrophy
  • Age-related sarcopenia (preclinical)
Considerations
  • Off-target effects on activin signaling (reproductive, cardiac) are a concern.
  • Not FDA-approved; banned by WADA.
Full Follistatin 344 profile →
Growth Hormone Axis
GHRP-2

Ghrelin-mimetic GH secretagogue with appetite effects.

Mechanism

A synthetic hexapeptide that activates the ghrelin/GHS-R1a receptor, stimulating endogenous GH release. Compared to Ipamorelin, GHRP-2 produces a stronger GH pulse but also modestly elevates cortisol, prolactin, and appetite.

Research areas
  • GH release in adult GH deficiency
  • Appetite stimulation in cachexia models
  • Diagnostic GH stimulation testing
Considerations
  • Not FDA-approved.
  • Less receptor-selective than Ipamorelin; expect appetite and cortisol effects.
  • Prohibited by WADA.
Full GHRP-2 profile →

Follistatin 344 vs GHRP-2 — Key differences

  • Class: Follistatin 344 is classified as Muscle · Myostatin Inhibition, while GHRP-2 is Growth Hormone Axis.
  • Primary research focus: Follistatin 344muscular dystrophy models; GHRP-2gh release in adult gh deficiency.
  • Tag: Muscle vs Growth hormone.

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