# Teriparatide (Forteo)

> Recombinant PTH(1-34) for severe osteoporosis.

Source: https://peptides.cafe/peptide/teriparatide
Category: Parathyroid Hormone · Anabolic Bone
Tag: FDA-Approved · Bone

## Mechanism
Recombinant fragment of parathyroid hormone (amino acids 1–34). Intermittent dosing stimulates osteoblast activity more than osteoclasts, producing net bone formation and increased bone mineral density.

## Research areas
- Postmenopausal osteoporosis
- Male osteoporosis
- Glucocorticoid-induced osteoporosis

## Common research protocols
- Daily injection: 20 mcg SC once daily for up to 2 years.

## Study summaries
- "Fracture Prevention Trial" — NEJM (2001): Reduced vertebral fractures by 65% in postmenopausal women.

## Considerations
- FDA-approved.
- Lifetime use limited to 2 years; transient hypercalcemia possible.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.