# Synthetic Secretin (ChiRhoStim)

> 27-amino-acid peptide used to stimulate pancreatic secretions for diagnosis.

Source: https://peptides.cafe/peptide/secretin-syn
Category: Diagnostic · Gastroenterology
Tag: FDA-Approved · Diagnostic

## Mechanism
Synthetic human secretin that stimulates pancreatic bicarbonate, fluid secretion, and gastrin release — used diagnostically for pancreatic function, gastrinoma evaluation, and ERCP facilitation.

## Research areas
- Pancreatic function testing
- Gastrinoma (Zollinger-Ellison) diagnosis
- ERCP facilitation

## Common research protocols
- Diagnostic: 0.2–0.4 mcg/kg IV bolus depending on indication.

## Study summaries
- "Secretin stimulation test for gastrinoma" — Gastroenterology (1989): Established as gold standard provocative test.

## Considerations
- FDA-approved.
- Single diagnostic dose; minimal adverse effects.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.