# Pramlintide (Symlin)

> Amylin analog adjunct to mealtime insulin.

Source: https://peptides.cafe/peptide/pramlintide
Category: Amylin Analog · Metabolic
Tag: FDA-Approved · Metabolic

## Mechanism
Synthetic analog of the pancreatic hormone amylin. Slows gastric emptying, suppresses inappropriate postprandial glucagon, and increases satiety as adjunct to insulin.

## Research areas
- Type 1 diabetes (with insulin)
- Type 2 diabetes on insulin

## Common research protocols
- Mealtime: 15–120 mcg SC before major meals (titrated).

## Study summaries
- "Pramlintide in T1D" — Diabetes Care (2003): Improved A1c and reduced postprandial glucose excursions.

## Considerations
- FDA-approved.
- Boxed warning: severe insulin-induced hypoglycemia.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.