# Humanin

> Mitochondrial-derived peptide studied for neuroprotection and metabolism.

Source: https://peptides.cafe/peptide/humanin
Category: Mitochondrial · Neuroprotection
Tag: Longevity

## Mechanism
A 24-amino-acid peptide encoded in mitochondrial DNA. Research suggests cytoprotective effects against Alzheimer's-related toxicity, improved insulin sensitivity, and modulation of apoptotic signaling.

## Research areas
- Neuroprotection (Alzheimer's models)
- Insulin sensitivity
- Cardiovascular protection in animal models

## Common research protocols
- Subcutaneous animal research: Investigational dosing in rodent models of aging and neurodegeneration.

## Study summaries
- "Humanin: a harbinger of mitochondrial-derived peptides" — Trends in Endocrinology & Metabolism (2013): Reviewed cytoprotective, metabolic, and longevity-relevant signaling.

## Considerations
- Early-stage research.
- No approved therapeutic use.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.