# Hexarelin

> Potent ghrelin-mimetic with cardiac research interest.

Source: https://peptides.cafe/peptide/hexarelin
Category: Growth Hormone Axis · Cardiac
Tag: Growth hormone

## Mechanism
A synthetic hexapeptide and potent GHS-R agonist. Stimulates GH release more strongly than GHRP-6 and shows cardioprotective signaling in preclinical ischemia-reperfusion models, partly independent of GH.

## Research areas
- GH release
- Cardiac ischemia-reperfusion (preclinical)
- Left ventricular function in animal models

## Common research protocols
- Short research cycles: Used in short subcutaneous cycles due to receptor desensitization with chronic use.

## Study summaries
- "Hexarelin and the cardiovascular system" — Cardiovascular Research (2006): Reviewed direct cardioprotective effects of hexarelin in animal models.

## Considerations
- Not FDA-approved.
- Tachyphylaxis with prolonged use.
- Prohibited by WADA.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.