# Glatiramer Acetate (Copaxone)

> Synthetic random peptide copolymer for relapsing multiple sclerosis.

Source: https://peptides.cafe/peptide/glatiramer-acetate
Category: Immunomodulator · Neurology
Tag: FDA-Approved · Neurology

## Mechanism
Random copolymer of L-glutamic acid, L-lysine, L-alanine, and L-tyrosine that mimics myelin basic protein, shifting T-cell responses toward anti-inflammatory Th2 profile and inducing regulatory T cells.

## Research areas
- Relapsing forms of multiple sclerosis
- Clinically isolated syndrome

## Common research protocols
- Daily 20 mg SC: 20 mg subcutaneously once daily.
- 40 mg three times weekly SC: 40 mg SC three times per week, ≥48 hours apart.

## Study summaries
- "Glatiramer acetate pivotal trials" — Neurology (1995): Reduced relapse rate in relapsing-remitting MS.

## Considerations
- FDA-approved.
- Injection-site reactions and transient post-injection chest tightness/flushing possible.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.