# GHRP-6

> Ghrelin-mimetic GH secretagogue researched for appetite and recovery.

Source: https://peptides.cafe/peptide/ghrp-6
Category: Growth Hormone Axis
Tag: Growth hormone · Appetite

## Mechanism
A hexapeptide ghrelin receptor (GHS-R1a) agonist that stimulates pituitary GH release and increases appetite via central ghrelin pathways. One of the earliest GH-releasing peptides studied.

## Research areas
- Endogenous GH pulse stimulation
- Appetite stimulation in cachexia models
- Cardioprotective signaling (preclinical)

## Common research protocols
- Pre-meal research dosing: Subcutaneous administration before meals in appetite-focused studies.

## Study summaries
- "GHRP-6 and the ghrelin receptor: cardiometabolic effects" — Cardiovascular Research (2010): Review of GH-independent cardioprotective signaling observed in animal models.

## Considerations
- Increases appetite and may elevate cortisol/prolactin more than newer secretagogues.
- Not FDA-approved; banned by WADA.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.