# GHRP-2

> Ghrelin-mimetic GH secretagogue with appetite effects.

Source: https://peptides.cafe/peptide/ghrp-2
Category: Growth Hormone Axis
Tag: Growth hormone

## Mechanism
A synthetic hexapeptide that activates the ghrelin/GHS-R1a receptor, stimulating endogenous GH release. Compared to Ipamorelin, GHRP-2 produces a stronger GH pulse but also modestly elevates cortisol, prolactin, and appetite.

## Research areas
- GH release in adult GH deficiency
- Appetite stimulation in cachexia models
- Diagnostic GH stimulation testing

## Common research protocols
- Stacked with GHRH analog: Combined with CJC-1295 or Sermorelin in research to amplify GH pulse amplitude.

## Study summaries
- "GHRP-2 stimulates GH release in healthy and GH-deficient adults" — Journal of Clinical Endocrinology & Metabolism (1997): Established robust GH response after subcutaneous administration.

## Considerations
- Not FDA-approved.
- Less receptor-selective than Ipamorelin; expect appetite and cortisol effects.
- Prohibited by WADA.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.