# Cetrorelix (Cetrotide) > GnRH antagonist used in IVF to prevent premature ovulation. Source: https://peptides.cafe/peptide/cetrorelix Category: GnRH Antagonist · Reproductive Tag: FDA-Approved · Fertility ## Mechanism Synthetic decapeptide that competitively blocks pituitary GnRH receptors, preventing LH surge during controlled ovarian stimulation. ## Research areas - IVF / controlled ovarian stimulation ## Common research protocols - IVF cycle: 0.25 mg SC daily, or single 3 mg dose during stimulation. ## Study summaries - "Cetrorelix in ART" — Human Reproduction (2000): Effective prevention of premature LH surge with simpler protocol than long agonist. ## Considerations - FDA-approved. - Used under specialist supervision. ## Disclaimer Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.