# Caspofungin (Cancidas)

> Echinocandin lipopeptide for invasive Candida and Aspergillus infections.

Source: https://peptides.cafe/peptide/caspofungin
Category: Echinocandin · Antifungal
Tag: FDA-Approved · Antifungal

## Mechanism
Semi-synthetic lipopeptide that inhibits β-1,3-D-glucan synthase, disrupting fungal cell wall integrity. First echinocandin approved.

## Research areas
- Invasive candidiasis
- Invasive aspergillosis (salvage)
- Empiric antifungal in febrile neutropenia

## Common research protocols
- Standard: 70 mg IV loading, then 50 mg IV daily.

## Study summaries
- "Caspofungin vs amphotericin B for invasive candidiasis" — NEJM (2002): Comparable efficacy with better tolerability.

## Considerations
- FDA-approved.
- Hepatic dose adjustment; few drug interactions.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.