# Calcitonin-Salmon (Miacalcin)

> 32-amino-acid peptide for osteoporosis and hypercalcemia.

Source: https://peptides.cafe/peptide/calcitonin-salmon
Category: Calcitonin · Bone Resorption
Tag: FDA-Approved · Bone

## Mechanism
Synthetic salmon calcitonin inhibits osteoclast-mediated bone resorption and promotes renal calcium excretion. Available as nasal spray or injection.

## Research areas
- Postmenopausal osteoporosis (>5 yrs postmenopause)
- Paget's disease
- Hypercalcemia

## Common research protocols
- Nasal spray: 200 IU intranasally daily, alternating nostrils.
- Injection: 100 IU SC/IM daily for Paget's.

## Study summaries
- "PROOF study" — American Journal of Medicine (2000): Reduced vertebral fracture risk in postmenopausal osteoporosis.

## Considerations
- FDA-approved.
- FDA cautions about possible malignancy signal with long-term use.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.