# BPC-157

> Body Protection Compound studied for gut and tissue support.

Source: https://peptides.cafe/peptide/bpc-157
Category: Tissue Repair · Gastrointestinal
Tag: Recovery

## Mechanism
A pentadecapeptide (15 amino acids) derived from a protective protein found in human gastric juice. Research suggests it modulates the nitric oxide system, upregulates growth hormone receptors in injured tissue, and promotes angiogenesis (formation of new blood vessels) — mechanisms associated with accelerated tendon, ligament, muscle, and intestinal mucosa repair in preclinical models.

## Research areas
- Tendon-to-bone healing
- Ligament and muscle recovery
- Gastric ulcer protection
- Inflammatory bowel models
- Neuroprotection (rodent)

## Common research protocols
- Localized injury research: Subcutaneous administration near affected site in animal models, typically 1–2× daily across short cycles.
- GI-focused research: Oral administration studied in rodent ulcer and IBD models.

## Study summaries
- "Pentadecapeptide BPC 157 and the central nervous system" — Neural Regeneration Research (2022): Review of neuroprotective and neurorepair signaling pathways observed in animal models.
- "Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia/reperfusion in rats" — Journal of Physiology - Paris (2018): Demonstrated mucosal protective effects and accelerated recovery from induced colitis.
- "BPC 157 and tendon-to-bone healing" — Journal of Orthopaedic Research (2010): Improved biomechanical recovery of transected Achilles tendons in rats.

## Considerations
- Human clinical trials are limited — most research is preclinical.
- Not FDA-approved for human therapeutic use.
- Quality, purity, and dosing of compounded peptides vary widely.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.