# 5-Amino-1MQ

> Small-molecule NNMT inhibitor researched for fat metabolism.

Source: https://peptides.cafe/peptide/5-amino-1mq
Category: Metabolic · Small Molecule
Tag: Metabolic

## Mechanism
Not a peptide but commonly grouped in peptide research. A selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in obese adipose tissue. Inhibition increases SAM and NAD+ availability, increasing adipocyte energy expenditure in animal models.

## Research areas
- Diet-induced obesity (rodent)
- White adipose tissue energy expenditure
- Age-related muscle function

## Common research protocols
- Oral research dosing: Daily oral dosing in animal obesity and aging studies.

## Study summaries
- "NNMT inhibition reduces adiposity in obese mice" — Nature Medicine (2015): Demonstrated weight loss and improved metabolic profile via NNMT inhibition.

## Considerations
- Investigational; no human clinical trials yet.
- Not FDA-approved.

## Disclaimer
Educational content only. Not medical advice, diagnosis, or treatment. Most research peptides are not FDA-approved for human therapeutic use. Consult a licensed clinician before any use.